Ruby Guis

Roundup found here

Shoooes

http://shoes.heroku.com
Windows compilation is a major hack project. See http://github.com/ashbb/shoes_hack_note

FXRuby

QT and QtRuby

Glimmer (Jruby/Swing)

Monkeybars (MVC for Jruby/Swing)

SproutCore (Apple’s JavaScriptGUI w/ Ruby bindings)

Limelight

Focused towards Form-Gui development.  No sprites!

wxWidgets / wxRuby

TK for Ruby

Tk has a known issue in OSX Leopard/SnowLeopard of sending new windows to background from script languages (Python, Ruby).  Not fixed as of 3/22/2010

RPG Maker XP w/ Ruby Game Scripting System

RubyGame

Rubygame requres custom ruby build w/ SDL libraries + custom wrapper execution 'rsdl'
Incompatible with spec / autospec.

Squeak / eToys / Scratch — Smalltalk

In-process w/ my 9-yo son!!