I've had to install Open thrice now on Vista x64, and these are the steps I've found that work 100% of the time.
First off, install Open using this link: http://www.mayhemgaming.net/ORPG1777/OpenRPG_Installer.exe
When it's done, and BEFORE you run Open for the first time (this is important): * Go to the Python25 directory under C:/, select Right-click on the python executable. * Click properties, then compatibility. * Check the box that reads 'Run this program as an administrator'. * Then do the same for pythonw.
Run Open for the first time using OpenRPG (Developer) in the start menu (this is also important).
If everything works, you're set. From then on you can use the normal OpenRPG shortcut in the start menu.
Hope this helps.
Thanks Sin for this installation Guide!!